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Sr. Manager, Quantitative Clinical Pharmacology

unlimited holidays - extra parental leave
Remote: 
Full Remote
Contract: 
Salary: 
132 - 165K yearly
Experience: 
Mid-level (2-5 years)
Work from: 
Massachusetts (USA), United States

Offer summary

Qualifications:

PhD in relevant field and 3+ years of experience in pharmacometrics or QSP modeling, Proficiency in R, NONMEM, Python, MATLAB or similar programming languages.

Key responsabilities:

  • Perform advanced pharmacometrics and disease progression analyses
  • Implement novel data analytics and collaborate with stakeholders
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Sarepta Therapeutics Biotech: Biology + Technology Large https://www.sarepta.com/
1001 - 5000 Employees
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Job description

The Sr. Manager, Quantitative Clinical Pharmacology is responsible for providing translational, clinical pharmacology and pharmacometric deliverables for development assets from pre-IND to Phase III. This incumbent will apply quantitative modeling methodologies inclusive of population PK, PKPD, quantitative system pharmacology (QSP), disease progression modeling using multivariate statistical and empirical approaches, as well as AI/ML based algorithms to integrate, analyze and interpret diverse data sources (e.g., pharmacokinetics, pharmacodynamics including biomarker & imaging, electronic health records).

Primary Responsibilities Include:

  • Perform advanced pharmacometrics, QSP and disease progression analyses and activities within assigned programs to yield high value population PK, PK/PD, QSP and disease progression modeling support for critical decision making
  • With guidance, implement novel data analytics and solutions for data visualizations, automation of analytics workflows for nonclinical and clinical data
  • With guidance, collaborate with stakeholders to co-develop data workflow and dashboards that facilitate centralized database and access, model utilization and output interpretation
  • Influence internal and external environment through publication and presentations at key scientific conferences and consortia

Desired Education and Skills:

  • PhD degree in pharmaceutical sciences, pharmacometrics, biomedical engineering, statistics, applied mathematics, or a related field with a minimum of 3 years of experience working as a pharmacometrician, or QSP modeler within pharmaceutical industry.
  • Experience in developing Population PK, PK/PD, exposure-response, QSP, disease progression modeling and other model based-analyses to aid in research and development decision making.
  • Proficiency in R, NONMEM, Python, MATALB or other similar programing languages.
  • Experience in developing advanced analytics that includes predictive, prescriptive & machine learning capabilities is a big plus
  • Excellent communication, multitasking, and collaboration skills
  • Experience in gene therapy and rare diseases is a plus, but not required.

#LI-TD1

#LI-Remote

This position is remote. However, you will be expected to work on site at one of Sarepta's facilities in the United States and/or attend Company-sponsored in-person events from time to time.

The targeted salary range for this position is $132,000 - $165,000 per year. Sarepta is making a good faith effort to be transparent and accurate around our hiring ranges. The salary offer is commensurate with Sarepta’s compensation philosophy and considers factors including, but not limited to, education, training, experience, external market conditions, criticality of role, and internal equity.

Candidates must be authorized to work in the U.S.

Sarepta Therapeutics offers a competitive compensation and benefit package.

Sarepta Therapeutics is an Equal Opportunity/Affirmative Action employer and participates in e-Verify.

Required profile

Experience

Level of experience: Mid-level (2-5 years)
Industry :
Biotech: Biology + Technology
Spoken language(s):
English
Check out the description to know which languages are mandatory.

Other Skills

  • Multitasking
  • Verbal Communication Skills
  • Organizational Skills

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