Executive Director, Medical Affairs Strategy - Oncology Portfolio

Arvinas is a clinical-stage biotechnology company dedicated to improving the lives of patients suffering from debilitating and life-threatening diseases through the discovery, development, and commercialization of therapies that degrade disease-causing proteins. Arvinas uses its proprietary PROTAC^® Discovery Engine platform to engineer proteolysis targeting chimeras, or PROTAC^® targeted protein degraders, that are designed to harness the body’s own natural protein disposal system to selectively and efficiently degrade and remove disease-causing proteins.

In addition to its robust preclinical pipeline of PROTAC protein degraders against validated and “undruggable” targets, the company has three investigational clinical-stage programs currently enrolling: vepdegestrant for the treatment of patients with locally advanced or metastatic ER+/HER2- breast cancer; ARV-102 for the treatment of patients with neurodegenerative disorders associated with LRRK2, and ARV-393 for the treatment of patients with relapsed/refractory non-Hodgkin Lymphoma and potentially other lymphomas.

In April 2024, Arvinas entered into a transaction with Novartis, including a global license agreement for the development and commercialization of the clinical stage PROTAC^® androgen receptor protein degrader ARV-766 for the treatment of prostate cancer. The transaction closed in May 2024.

#TeamArvinas is made up of approximately 450 passionate and curious employees, whose diverse thoughts and perspectives are highly valued. Arvinas employees embrace the freedom to pursue innovation, think creatively, and give back. They are driven by the company’s values and mission – to improve the lives of patients with serious diseases by pioneering therapies created with our revolutionary PROTAC® protein degradation platform. We’re really excited about the work we’re doing inside and outside of Arvinas, and think you will be, too. But don’t just take our word for it – learn more about life at Arvinas and what employees have to say.

For more information, please visit www.arvinas.com.

Position Summary

Arvinas has an outstanding opportunity for an experienced medical affairs leader to play a pivotal role in shaping medical affairs strategy and tactical plans for the Arvinas oncology portfolio. The Executive Director is a key member of the Medical Affairs Leadership Team and will manage the medical strategy team, consisting of medical directors and a patient advocacy director, working across the oncology portfolio. The Executive Director will provide strategic input into the oncology global asset teams, either directly or through oversight of the medical strategy team members assigned to the asset teams. This role will also ensure medical affairs launch readiness as we prepare for the launch of Arvinas’ first product. The Executive Director will collaborate with cross-functional leaders across the organization including those in clinical development, commercial, regulatory, corporate communications and investor relations. 

The Executive Director will report to the Vice President of Medical Affairs, and will be located remotely from a location within the U.S.

Principal Responsibilities

Key responsibilities of this role include, but are not limited to:

• Lead, mentor, and develop the medical strategy team consisting of medical directors and a patient advocacy director working across the oncology portfolio
• Oversee the development and execution of medical affairs strategy and plans to support the Arvinas oncology portfolio across all stages – from early development to launch and throughout the product lifecycle
• Ensure medical affairs launch readiness
• Serve as Core member and/or oversee medical strategy team members on the global asset teams (development teams)
• Oversee the implementation and functioning of the asset-specific medical sub-teams (MSTs) to develop and execute on medical strategies and tactics
• Provide cross-portfolio medical affairs representation on the publication planning committees. Participate in data analysis efforts, and lead in manuscript, abstract, and poster development
• Oversee cross-portfolio medical affairs research program (including collaborative studies, investigator sponsored research, and HEOR/RWD studies in partnership with HEOR Lead)
• Collaborate closely with medical affairs functions including those in scientific communications, publications, field medical, health outcomes and economic research, and medical affairs operations
• Collaborate closely cross-functional partners including those in clinical development, clinical operations, commercial, translational, corporate communications, and investor relations
• Model leadership behaviors consistent with Arvinas values

Qualifications

• 15 years of relevant oncology experience, with at least 10 years of Medical Affairs experience in pharmaceutical/biopharmaceutical industry
• Matrix team leadership required, candidates with direct managerial experience highly preferred
• Demonstrated ability to think strategically and translate medical affairs strategy into an actionable plan
• Strong interpersonal skills and excellent verbal communication and presentation skills.
• Proven ability to facilitate open discussion and debate among key stakeholders and build internal and external relationships.
• Well-organized with the ability to be flexible, prioritize multiple demands, and effectively lead in a matrix organization.
• Growth mindset with demonstrated ability to perform player-coach activities
• Proficiency in clinical trial data review and interpretation
• Ideal candidate has both US and Global medical affairs experience and breast cancer experience.
• Ability to travel 20% of time
• Remote (Home office based): The duties of this role are generally conducted in a home office environment. Employees must be able, with or without an accommodation to use a computer; engage in communications via phone, video, and electronic messaging; engage in problem solving and non-linear thought, analysis, and dialogue; collaborate with others; maintain general availability during standard business hours. 
• Must be legally authorized to work in the US without the need for employer sponsorship now or at any time in the future.

Education

• MD, PhD, or PharmD required

#LI-Remote

 Arvinas is proud to offer a competitive package of base and incentive compensation as well as a comprehensive benefits program designed to support the health, wellness and financial security of our employees and their families. Benefits include group medical, vision and dental coverage, group and supplemental life insurance, and much more. To learn more about Arvinas, please visit www.arvinas.com

Arvinas is an Equal Opportunity Employer