Senior Computational Biologist / Bioinformatician

Overview

Senior Computaional Biologist

US Remote

Emmes Group: Building a better future for us all.

Emmes Group is transforming the future of clinical research, bringing the promise of new medical discovery closer within reach for patients. Emmes Group was founded as Emmes more than 47 years ago, becoming one of the primary clinical research providers to the US government before expanding into public-private partnerships and commercial biopharma. Emmes has built industry leading capabilities in cell and gene therapy, vaccines and infectious diseases, ophthalmology, rare diseases, and neuroscience.

We believe the work we do will have a direct impact on patients’ lives and act accordingly. We strive to build a collaborative culture at the intersection of being a performance and people driven company. We’re looking for talented professionals eager to help advance clinical research as we work to embed innovation into the fabric of our company. If you share our motivations and passion in research, come join us!

Primary Purpose

This position supports "Essex, an Emmes Company". Essex is a biomedical informatics and health information technology-focused consultancy founded in 2009 and headquartered in Rockville, MD. The Essex team comprises experts with extensive experience in strategically developing and managing complex health and biomedical information programs for clients in the Federal Government, research academia, and private sectors.

The Senior Computational Biologist leads the Computational Biology and Data Science team at Essex. S/he will be part of a fast-paced, cross-functional team of biologists, physicians, bioinformaticians, and software developers working at our client’s site on the leading-edge of precision oncology.

The Senior Computational Biologist:

• will serve as a subject matter expert in the field of biological data curation and data modelling
• will contribute to the design and development of databases and pipelines being built to store and analyze clinical data
• will lead the design of websites that our end users use to interact with our data resources
• will interface with participating clinical labs to ensure that data on patients are correctly loaded into the Precision Medicine Initiative data processing infrastructure
• will develop timely and accurate clinical reports for our various stakeholders
  
  

Responsibilities

• Serve as a subject matter expert in the field of biological data curation and data modelling
• Contribute to the design and development of databases being built to store clinical data
• Lead the design and implementation of NGS clinical data pipelines
• Interface with participating clinical labs to ensure that data on patients are correctly loaded into the MATCH data processing infrastructure
• Develop timely and accurate clinical analysis reports for our various stakeholders
  
  

Qualifications

• Proficient in scripting languages (Python, R etc.) and snakemake
• An understanding of clinical NGS data analysis features and pipeline development for analysis (WES, RNASeq, ATAQSeq, Single Cell, Long Read, etc)
• Effective communication skills for presentations to federal stakeholders, engineers and other bioinformaticians.
• Familiarity with code versioning software: SVN, Git
  
  

Required Experience:

• An terminal degree in the Biology, Bioinformatics or Computer Science.
• In addition to educational requirement, a minimum of six (6) years of progressively responsible job-related experience including two (2) years of experience in a leadership capacity.
• A deep familiarity with Biology, Medical Genetics and the curation of medically relevant human disease variants.
• A thorough understanding of the biological data curation process, including the importance of data provenance, levels of evidence; ontologies and controlled vocabularies used to annotate biological and clinical data.
  
  

Why work at Emmes?

At Emmes, your actions and hard work will have a direct impact on public health initiatives, both globally and in our local communities with opportunities for volunteerism through our Emmes Cares community engagement program. We offer a competitive benefits package focused on the health and needs of our growing workforce, including:

• Flexible Approved Time Off
• Tuition Reimbursement
• 401k Retirement Plan
• Work From Home Anywhere in the US
• Maternal/Paternal Leave
• Casual Dress Code & Work Environment
  
  

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The Emmes Company, LLC is an equal opportunity affirmative action employer and does not discriminate in its selection and employment practices. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, political affiliation, sexual orientation, gender identity, marital status, disability, protected veteran status, genetic information, age, or other legally protected characteristics.