Offer summary

Qualifications:

Advanced degree in pharmacology, pharmacometrics, or a related field., Strong expertise in quantitative systems pharmacology and modeling techniques., Experience in clinical drug development and regulatory processes., Proficient in data analysis and interpretation, particularly in pharmacokinetics and pharmacodynamics..

Key responsibilities:

Develop and apply quantitative systems pharmacology models for evaluating novel targets and compounds.

Lead pharmacometrics initiatives and collaborate on model informed drug development plans.

Conduct quantitative analyses to optimize dosing and study designs in clinical trials.

Act as a Subject Matter Expert, providing training and support in quantitative methodologies and processes.

Job description

When our values align, there's no limit to what we can achieve.

At Parexel, we all share the same goal - to improve the world's health. From clinical trials to regulatory, consulting, and market access, every clinical development solution we provide is underpinned by something special - a deep conviction in what we do.

Each of us, no matter what we do at Parexel, contributes to the development of a therapy that ultimately will benefit a patient. We take our work personally, we do it with empathy and we're committed to making a difference.

Quantitative Systems Pharmacologist

KEY RESPONSIBILITIES:

The Quantitative Systems Pharmacologist is responsible for the development and application of QSP models for the in silico evaluation of novel targets and compounds, including preclinical and clinical study design and mechanistic interpretation of results. This individual integrates and shares data and knowledge in a highly stimulating, collaborative, and multi-disciplinary environment to develop a quantitative understanding of physiological systems and disease mechanisms within and across therapeutic areas.

Minimum Requirements

1,Provides pharmacometrics expertise and leadership to projects.

2,Develops model informed drug development (MIDD) plans across projects and disease areas in order to optimize prospective studies, inform drug development strategy and project decision-making, in collaboration with partners.

3,Conducts and reports quantitative analyses which integrate knowledge of pharmacokinetics, pharmacodynamics, patient characteristics, and disease states to optimize doses, dosage regimens and study designs throughout clinical drug development.

4,Identifies opportunities where modeling and simulation can advance the understanding of pharmacological activity, efficacy and safety.

5,Acts as pharmacometrics Subject Matter Expert (SME), including proactive support and development of quantitative methodology, software, hardware, and related business processes, in addition to training to the the global clinical pharmacology organization.

Required profile