We are seeking applications from experienced industry, startup and/or new science-based technology development professionals from anywhere in the world to work with us on a novel technology that uses unexploited biology to unlock protein production with applications in biomanufacturing and therapeutics.
This role is full-time, starting asap and fully remote until venture incorporation and spin-out, date TBD.
THE OPPORTUNITY:
Low transgene expression and loss of transgene expression over time is a significant challenge for the biomanufacturing industry, as well as a bottleneck for cell and gene therapy development. For the production of proteins , declining transgene expression over time reduces product titres, increases production costs and can prevent viable products from being made at all. In a world that is moving towards biomanufacturing, solving this challenge has the potential to unlock the full potential of biomanufacturing applications, enabling their development and increasing scaling efficiency. With biologics revenue poised to overtake small molecule revenue globally in the coming years, and cell and gene therapies in its infancy, this is a challenge worth solving from a therapeutic and commercial perspective.
OUR APPROACH:
In contrast to current transgene optimisation tactics, we are learning from nature, leveraging novel and proprietary insights from human genetic elements which have evolved over millions of years. Buoyed by exciting proof of concept data, we are developing wet lab and computational systems to apply these novel mechanisms to biomanufacturing. Our mission is to significantly improve recombinant protein titres, increasing scaling efficiency and allowing difficult-to-express proteins to be commercially scaled for the first time.
Requirements
Preferred (nice-to-have):
Benefits
We use our unique venture creation process to create, spin-out and invest into science companies, combining available scientific knowledge and founder-type scientists into high-impact ventures.
We operate in 4 sectors: Pharmaceuticals, Climate, Agriculture and Computation, tackling the challenges defining those areas by taking a first principles approach and partnering with leading institutions.
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